A blockage in which type of artery is most likely to result in a myocardial infarction?

A blockage in the coronary artery is the most likely to result in a myocardial infarction because the coronary arteries are specifically responsible for supplying blood to the heart muscle itself. When there is a blockage in these arteries, typically due to the buildup of plaque (atherosclerosis), the flow of oxygenated blood to a portion of the heart is restricted. This can lead to the heart muscle becoming ischemic (lacking oxygen), and eventually, if the blockage persists, it can result in tissue death, or infarction.

In contrast, blockages in the cerebral artery can lead to strokes, specifically ischemic strokes, but not heart attacks. Blockages in the pulmonary artery can result in pulmonary embolism, which affects blood flow to the lungs rather than the heart. Lastly, a blockage in the femoral artery primarily impacts blood flow to the lower limbs and can lead to peripheral artery disease but does not directly cause myocardial infarction. Thus, the primary role of the coronary arteries in heart function makes them the critical factor in the occurrence of a myocardial infarction.